Analisa Penyakit Kandung dan Saluran Empedu serta Kaitannya dengan Usia dan Status Infeksi di Rumah Sakit Mitra Keluarga Kalideres Periode 2018 - 2023

Yonathan Adi Purnomo, Fernando Nathaniel, Dean Ascha Wijaya, William Gilbert Satyanegara, Yohanes Firmansyah

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ABSTRACT

 

Biliary system diseases are relatively common digestive conditions. Gallstones affect approximately 10-15% of the world's population and vary based on sociodemographic factors. This cross-sectional study aims to determine proportions of gallbladder and bile duct diseases, with or without gallstones and infections at Mitra Keluarga Kalideres Hospital, selected based on specific criteria using medical record data from the period between 2018 and June 2023, considering the final diagnoses of respondents. Variables in this study include gender, age, biliary anatomical abnormalities (gallbladder, bile duct, or nonspecific), gallstone incidence, and incidence of infections in biliary anatomical region. Statistical analysis used Independent T-Test. Out of 3916 respondents, the average age was 51.73 years, and majority were females (67.6%). 470 patients experienced infections in gallbladder and/or bile duct. There was a significant association between age groups and infection status (p<0.001) and anatomical location (p<0.001). The <45 age group had a 1.975 times higher risk of biliary system infection, while the >45 age group had a 2.165 times higher risk of bile duct disease compared to the <45 age group. The results of the Independent T-Test indicated a significant difference in the average age between the groups with and without biliary system infections (p-value < 0.001).

 

Keywords: Bile duct, Infection, Gall bladder, Gallstones

 

 

ABSTRAK

 

Penyakit sistem bilier merupakan kondisi digestif yang cukup sering. Batu empedu menyerang kurang lebih 10-15% populasi di dunia dan bervariasi dari faktor sosiodemografi. Penelitian potong lintang ini bertujuan untuk mengetahui proporsi dari penyakit kandung empedu, saluran empedu, dengan atau tanpa batu empedu dan infeksi di Rumah Sakit Mitra Keluarga Kalideres yang dipilih sesuai kriteria menggunakan data rekam medis pada periode waktu 2018 hingga Juni 2023 dengan melihat diagnosa akhir responden. Variabel dalam penelitian ini yaitu jenis kelamin, usia, anatomi kelainan empedu (kandung empedu, saluran empedu, atau tidak spesifik), insidensi batu empedu, dan insidensi infeksi daerah anatomi empedu. Analisis statistik menggunakan uji Independent T-Test. Dari 3916 responden, rerata usia adalah 51,73 tahun dan didominasi oleh perempuan (67,6%). 470 pasien mengalami infeksi pada kandung empedu dan atau saluran empedu. Didapatkan hubungan yang bermakna antara kelompok usia terhadap status infeksi (p<0,001) dan lokasi anatomis (p<0,001). Kelompok usia <45 tahun berisiko 1,975 kali untuk mengalami infeksi pada sistem bilier namun kelompok usia >45 tahun berisiko 2,165 kali untuk mengalami sakit di saluran empedu dibandingkan kelompok usia <45 tahun. Hasil uji Independent T-Test didapatkan bahwa terdapat perbedaan rerata usia yang bermakna antara kelompok dengan infeksi dan tanpa infeksi pada sistem bilier (p-value < 0,001).

 

Kata kunci: Batu Empedu, Infeksi, Kandung Empedu, Saluran Empedu


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DOI: https://doi.org/10.33024/mahesa.v3i10.11321

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