A Review on the Effect of Cell Phone Electromagnetic Radiation on Histological Testicles

Irsandi Rizki Farmananda, Irmawan Farindra, Ni Made Linawati

Sari


ABSTRACT

 

Cell phones have become an essential possession for individuals in today's society. Nevertheless, beneath their widespread use lies a potential hazard in the form of electromagnetic radiation. The level of radiation emitted varies, along with its impact on the human body, particularly on the reproductive system. This research aims to consolidate findings from existing studies on the influence of cell phone electromagnetic radiation on the histological makeup of the testes. A review of literature was conducted following a PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) approach, utilizing the PubMed and Scopus journal publication databases. A total of 133 articles were identified through the database search, with inclusion and exclusion criteria established based on the PICOS framework. Following the screening process, six articles met the predetermined criteria and were deemed suitable for analysis. The results of the study demonstrate that exposure to electromagnetic radiation led to alterations in the histological structure of the testes in experimental animals. In conclusion, prolonged exposure to electromagnetic radiation has an impact on the histological composition of the testes in experimental animals.

 

Keywords: Electromagnetic Radiation, Histology, Testicles, Cell Phone


Referensi


Adebayo, E. A., Adeeyo, A. O., Ogundiran, M. A., & Olabisi, O. (2019). Bio-physical effects of radiofrequency electromagnetic radiation (RF-EMR) on blood parameters, spermatozoa, liver, kidney and heart of albino rats. Journal of King Saud University - Science, 31(4), 813–821. https://doi.org/10.1016/j.jksus.2018.11.007

Agarwal, H., & Agarwal, R. (2017). First Industrial Revolution and Second Industrial Revolution: Technological Differences and the Differences in Banking and Financing of the Firms. Saudi Journal of Humanities and Social Sciences, 2(11A), 1062–1066. https://doi.org/10.21276/sjhss.2017.2.11.7

Aitken, R. J., & Baker, M. A. (2020). The Role of Genetics and Oxidative Stress in the Etiology of Male Infertility—A Unifying Hypothesis? Frontiers in Endocrinology, 11, 581838. https://doi.org/10.3389/FENDO.2020.581838/BIBTEX

Barati, M., Darvishi, B., Javidi, M. A., Mohammadian, A., Shariatpanahi, S. P., Eisavand, M. R., & Madjid Ansari, A. (2021). Cellular stress response to extremely low-frequency electromagnetic fields (ELF-EMF): An explanation for controversial effects of ELF-EMF on apoptosis. Cell Proliferation, 54(12), e13154. https://doi.org/10.1111/CPR.13154

Bilmez, Y., & Ozturk, S. (2023). Dynamic changes of histone methylation in male germ cells during spermatogenesis. F&S Reviews, 4(3), 187–205. https://doi.org/10.1016/J.XFNR.2023.07.001

Bin-Meferij, M. M., & El-Kott, A. F. (2015). The radioprotective effects of Moringa oleifera against mobile phone electromagnetic radiation-induced infertility in rats. International Journal of Clinical and Experimental Medicine, 8(8), 12487. /pmc/articles/PMC4612844/

D’Agostino, S., & D’Agostino, S. (2016). An Overview of the Nineteenth and Twentieth Centuries’ Theories of Light, Ether, and Electromagnetic Waves. Advances in Historical Studies, 5(1), 1–11. https://doi.org/10.4236/AHS.2016.51001

Darbandi, M., Darbandi, S., Agarwal, A., Sengupta, P., Durairajanayagam, D., Henkel, R., & Sadeghi, M. R. (2018). Reactive oxygen species and male reproductive hormones. Reproductive Biology and Endocrinology 2018 16:1, 16(1), 1–14. https://doi.org/10.1186/S12958-018-0406-2

De Felice, F., Marchetti, C., Marampon, F., Cascialli, G., Muzii, L., & Tombolini, V. (2019). Radiation effects on male fertility. Andrology, 7(1), 2–7. https://doi.org/10.1111/andr.12562

Eldawlatly, A., Alshehri, H., Alqahtani, A., Ahmad, A., Al-Dammas, F., & Marzouk, A. (2018). Appearance of Population, Intervention, Comparison, and Outcome as research question in the title of articles of three different anesthesia journals: A pilot study. Saudi Journal of Anaesthesia, 12(2), 283. https://doi.org/10.4103/SJA.SJA_767_17

Feychting, M., Schüz, J., Toledano, M. B., Vermeulen, R., Auvinen, A., Harbo Poulsen, A., Deltour, I., Smith, R. B., Heller, J., Kromhout, H., Huss, A., Johansen, C., Tettamanti, G., & Elliott, P. (2024). Mobile phone use and brain tumour risk – COSMOS, a prospective cohort study. Environment International, 185, 108552. https://doi.org/10.1016/J.ENVINT.2024.108552

Gautam, R., Singh, K. V., Nirala, J., Murmu, N. N., Meena, R., & Rajamani, P. (2019). Oxidative stress-mediated alterations on sperm parameters in male Wistar rats exposed to 3G mobile phone radiation. Andrologia, 51(3). https://doi.org/10.1111/AND.13201

Ginting, M. D. (2019). Penggunaan Telepon Genggam pada Masyarakat Perbatasan (Survei pada Kecamatan Tanjung Beringin, Kabupaten Serdang Bedagai, Provinsi Sumatera Utara). Jurnal PIKOM (Penelitian Komunikasi Dan Pembangunan), 20(1), 58–69. https://doi.org/10.31346/JPIKOM.V20I1.1906

Gong, E. J., Shin, I. S., Son, T. G., Yang, K., Heo, K., & Kim, J. S. (2014). Low-dose-rate radiation exposure leads to testicular damage with decreases in DNMT1 and HDAC1 in the murine testis. Journal of Radiation Research, 55(1), 54. https://doi.org/10.1093/JRR/RRT090

Gye, M. C., & Park, C. J. (2012). Effect of electromagnetic field exposure on the reproductive system. In Clinical and Experimental Reproductive Medicine (Vol. 39, Issue 1, pp. 1–9). https://doi.org/10.5653/cerm.2012.39.1.1

Hasan, I., Amin, T., Alam, M. R., & Islam, M. R. (2021). Hematobiochemical and histopathological alterations of kidney and testis due to exposure of 4G cell phone radiation in mice. Saudi Journal of Biological Sciences, 28(5), 2933–2942. https://doi.org/10.1016/J.SJBS.2021.02.028

Hassanzadeh-Taheri, M., Khalili, M. A., Hosseininejad Mohebati, A., Zardast, M., Hosseini, M., Palmerini, M. G., & Doostabadi, M. R. (2022). The detrimental effect of cell phone radiation on sperm biological characteristics in normozoospermic. Andrologia, 54(1). https://doi.org/10.1111/AND.14257

Hatch, E. E., Willis, S. K., Wesselink, A. K., Mikkelsen, E. M., Eisenberg, M. L., Sommer, G. J., Sorensen, H. T., Rothman, K. J., & Wise, L. A. (2021). Male cellular telephone exposure, fecundability, and semen quality: results from two preconception cohort studies. Human Reproduction (Oxford, England), 36(5), 1395. https://doi.org/10.1093/HUMREP/DEAB001

Hossaini, H., Khodadoost, F., & Goftari, S. (2023). Specific absorption rate of different phone brands and health students’ awareness, attitude, and performance towards mobile phone hazards. Environmental Health Engineering And Management Journal, 10(2), 149–156. https://doi.org/10.34172/EHEM.2023.17

Hu, C., Zuo, H., & Li, Y. (2021). Effects of Radiofrequency Electromagnetic Radiation on Neurotransmitters in the Brain. Frontiers in Public Health, 9, 691880. https://doi.org/10.3389/FPUBH.2021.691880/BIBTEX

ICNIRP. (2020). Guidelines for Limiting Exposure to Electromagnetic Fields (100 kHz to 300 GHz). Health Physics, 118(5), 483–524. https://doi.org/10.1097/HP.0000000000001210

Jabeen, S., Haq, A. A., Nigar, S., Iqbal, S., Sarwat, S., & Mubeen, S. (2021). Electromagnetic Radiation from Cell Phones: A Contributing Factor to Male Infertility. Medical Form Monthly, 32(8). https://www.medforum.rtfstudio.com.pk/article/1electromagnetic-radiation-from-cell-phones-a-contributing-factor-to-male-infertility

Ji, H. J., Wang, D. M., Wu, Y. P., Niu, Y. Y., Jia, L. L., Liu, B. W., Feng, Q. J., & Feng, M. L. (2016). Wuzi Yanzong pill, a Chinese polyherbal formula, alleviates testicular damage in mice induced by ionizing radiation. BMC Complementary and Alternative Medicine, 16(1). https://doi.org/10.1186/S12906-016-1481-6

Jin, Z. (2023). Analysis of electromagnetic wave applications and development. Highlights in Science, Engineering and Technology, 68, 172–181. https://doi.org/10.54097/HSET.V68I.12061

Karaca, S. (2023). Children are more Exposed to Electromagnetic Radiation in COVID-19 Lockdown: A Literature Review. The Indonesian Journal of Public Health, 18(1), 169–178. https://doi.org/10.20473/IJPH.V18I1.2023.169-178

Karger, C. P. (2005). Mobile phones and health: a literature overview. Zeitschrift Fur Medizinische Physik, 15(2), 73–85. https://doi.org/10.1078/0939-3889-00248

Kesari, K. K., Agarwal, A., & Henkel, R. (2018). Radiations and male fertility. Reproductive Biology and Endocrinology : RB&E, 16(1). https://doi.org/10.1186/S12958-018-0431-1

Koohestanidehaghi, Y., Khalili, M. A., Dehghanpour, F., & Seify, M. (2024). Detrimental impact of cell phone radiation on sperm DNA integrity. Clinical and Experimental Reproductive Medicine, 51(1), 13. https://doi.org/10.5653/CERM.2023.06121

Kumar, L. R., Chii, K. D., Way, L. C., Jetly, Y., Rajendaran, V., Kumar, L. R., Chii, K. D., Way, L. C., Jetly, Y., & Rajendaran, V. (2011). Awareness of mobile phone hazards among university students in a Malaysian medical school. Health, 3(7), 406–415. https://doi.org/10.4236/HEALTH.2011.37068

Lathiifah, D. A., Qodariah, L., & Abidin, F. A. (2023). Problematic Smartphone Use in Adolescents: Parental Structure and Parental Psychological Controls as Predictors. Jurnal Ilmu Keluarga Dan Konsumen, 16(1), 50–60. https://doi.org/10.24156/JIKK.2023.16.1.50

Liu, L., Huang, B., Lu, Y., Zhao, Y., Tang, X., & Shi, Y. (2024). Interactions between electromagnetic radiation and biological systems. IScience, 27(3), 109201. https://doi.org/10.1016/J.ISCI.2024.109201

Ma, J., Dong, S., Lu, H., Chen, Z., Yu, H., Sun, X., Peng, R., Li, W., Wang, S., Jiang, Q., Li, F., & Ma, L. (2022). The hydrogen storage nanomaterial MgH2 improves irradiation-induced male fertility impairment by suppressing oxidative stress. Biomaterials Research, 26(1). https://doi.org/10.1186/S40824-022-00266-6

Maffei, M. E. (2022). Magnetic Fields and Cancer: Epidemiology, Cellular Biology, and Theranostics. International Journal of Molecular Sciences, 23(3). https://doi.org/10.3390/IJMS23031339/S1

Maluin, S. M., Osman, K., Jaffar, F. H. F., & Ibrahim, S. F. (2021). Effect of Radiation Emitted by Wireless Devices on Male Reproductive Hormones: A Systematic Review. Frontiers in Physiology, 12, 732420. https://doi.org/10.3389/FPHYS.2021.732420/FULL




DOI: https://doi.org/10.33024/mahesa.v4i12.15546

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