Hubungan Karakteristik Faktor Sosioekonomi Dengan Masa Survival Pasien Kanker Kolorektal Di Rumah Sakit Umum Daerah Nganjuk, Jawa Timur

Muhammad Imam Lebdo Husodo, Budiono Raharjo, Pratika Yuhyi Hernanda, Maria Widijanti Sugeng, Erny Erny, Anton Sumarpo

Sari


Kanker kolorektal merupakan suatu kegansan yang bermula dari jaringan mukosa usus besar, yang secara struktur terdiri dari kolon dan/atau rectum. Hingga saat ini, insiden kanker kolorektal menduduki urutan ketiga dari seluruh jenis kanker di dunia. Penelitian ini bertujuan untuk mencari hubungan dan memberikan gambaran mengenai factor sosioekonomi meliputi variable status perkawinan, status bekerja, status pendidikan, dan masa survival pada pasien kanker kolorektal di Rumah Sakit Umum Daerah (RSUD) Nganjuk. Penelitian ini menggunakan desain penelitian deskriptif analitik. Data dikumpulkan dari rekam medis pasien kanker kolorektal yang dirawat di RSUD Nganjuk. Analisis dilakukan menggunakan uji statistik Kaplan-Meier dan log-rank test untuk menganalisa gambaran factor sosioekonomi dengan masa survival pasien kanker kolorektal di RSUD Nganjuk. Terdapat gambaran masa survival yang cenderung lebih baik pada pasien berstatus menikah, bekerja, dan berpendidikan di bawah SLTA. Meskipun hasil penelitian menunjukkan hubungan yang tidak signifikan, didapatkan gambaran masa survival yang lebih baik pada variabel pasien dengan kategori menikah, bekerja, dan pendidikan di bawah SLTA.


Kata Kunci


Kanker kolorektal; Masa survival; Status sosioekonomi

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Referensi


Aizer, A. A., Chen, M.-H., McCarthy, E. P., Mendu, M. L., Koo, S., Wilhite, T. J., Graham, P. L., Choueiri, T. K., Hoffman, K. E., Martin, N. E., Hu, J. C., & Nguyen, P. L. (2013). Marital Status and Survival in Patients With Cancer. Journal of Clinical Oncology, 31(31), 3869–3876. https://doi.org/10.1200/JCO.2013.49.6489

Allison, J. E., Tekawa, I. S., Ransom, L. J., & Adrain, A. L. (1996). A Comparison of Fecal Occult-Blood Tests for Colorectal-Cancer Screening. New England Journal of Medicine, 334(3). https://doi.org/10.1056/nejm199601183340304

Alyabsi, M., Ramadan, M., Algarni, M., Alshammari, K., & Jazieh, A. R. (2021). The effect of marital status on stage at diagnosis and survival in Saudis diagnosed with colorectal cancer: cancer registry analysis. Scientific Reports, 11(1), 8603. https://doi.org/10.1038/s41598-021-88042-9

Bishehsari, F., Mahdavinia, M., Vacca, M., Malekzadeh, R., & Mariani-Costantini, R. (2014). Epidemiological transition of colorectal cancer in developing countries: Environmental factors, molecular pathways, and opportunities for prevention. World Journal of Gastroenterology, 20(20), 6055–6072. https://doi.org/10.3748/wjg.v20.i20.6055

Bultman, S. J. (2017). Interplay between diet, gut microbiota, epigenetic events, and colorectal cancer. Molecular Nutrition and Food Research, 61(1). https://doi.org/10.1002/mnfr.201500902

Carethers, J. M., & Doubeni, C. A. (2020). Causes of Socioeconomic Disparities in Colorectal Cancer and Intervention Framework and Strategies. Gastroenterology, 158(2), 354–367. https://doi.org/10.1053/j.gastro.2019.10.029

Chan, D. S. M., Lau, R., Aune, D., Vieira, R., Greenwood, D. C., Kampman, E., & Norat, T. (2011). Red and processed meat and colorectal cancer incidence: Meta-analysis of prospective studies. PLoS ONE, 6(6). https://doi.org/10.1371/journal.pone.0020456

Dekker, E., Tanis, P. J., Vleugels, J. L. A., Kasi, P. M., & Wallace, M. B. (2019). Colorectal cancer. Lancet (London, England), 394(10207), 1467–1480. https://doi.org/10.1016/S0140-6736(19)32319-0

den Bakker, C. M., Anema, J. R., Huirne, J. A. F., Twisk, J., Bonjer, H. J., & Schaafsma, F. G. (2020). Predicting return to work among patients with colorectal cancer. Journal of British Surgery, 107(1), 140–148. https://doi.org/10.1002/bjs.11313

Haviland, J., Sodergren, S., Calman, L., Corner, J., Din, A., Fenlon, D., Grimmett, C., Richardson, A., Smith, P. W., Winter, J., & Foster, C. (2017). Social support following diagnosis and treatment for colorectal cancer and associations with health‐related quality of life: Results from the UK ColoREctal Wellbeing (CREW) cohort study. Psycho-Oncology, 26(12), 2276–2284. https://doi.org/10.1002/pon.4556

Keum, N., & Giovannucci, E. (2019). Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nature Reviews Gastroenterology & Hepatology, 16(12), 713–732. https://doi.org/10.1038/s41575-019-0189-8

Liu, X., Zhang, X., Ruan, G., Zheng, X., Chen, Y., Zhang, X., Liu, T., Ge, Y., & Shi, H. (2024). Relationship between educational level and survival of patients with cancer: A multicentre cohort study. Cancer Medicine, 13(7). https://doi.org/10.1002/cam4.7141

Liu, Y., Zhang, C., Wang, Q., Wu, K., Sun, Z., Tang, Z., & Zhang, B. (2023). Temporal Trends in the Disease Burden of Colorectal Cancer with Its Risk Factors at the Global and National Level from 1990 to 2019, and Projections Until 2044. Clinical Epidemiology, 15. https://doi.org/10.2147/CLEP.S388323

Massaut, E., Hendlisz, B., & Klastersky, J. A. (2019). The close interrelation between colorectal cancer, infection and microbiota. Current Opinion in Oncology, 31(4), 362–367. https://doi.org/10.1097/CCO.0000000000000543

Morgan, E., Arnold, M., Gini, A., Lorenzoni, V., Cabasag, C. J., Laversanne, M., Vignat, J., Ferlay, J., Murphy, N., & Bray, F. (2023). Global burden of colorectal cancer in 2020 and 2040: Incidence and mortality estimates from GLOBOCAN. Gut, 72(2). https://doi.org/10.1136/gutjnl-2022-327736

Nishihara, R., Wu, K., Lochhead, P., Morikawa, T., Liao, X., Qian, Z. R., Inamura, K., Kim, S. A., Kuchiba, A., Yamauchi, M., Imamura, Y., Willett, W. C., Rosner, B. A., Fuchs, C. S., Giovannucci, E., Ogino, S., & Chan, A. T. (2013). Long-Term Colorectal-Cancer Incidence and Mortality after Lower Endoscopy. New England Journal of Medicine, 369(12). https://doi.org/10.1056/nejmoa1301969

Plummer, J. M., Leake, P. A., Ferron-Boothe, D., Roberts, P. O., Mitchell, D. I., & McFarlane, M. E. (2016). Colorectal cancer survival in Jamaica. Annals of Medicine and Surgery, 6. https://doi.org/10.1016/j.amsu.2016.01.018

Sharma, R., Abbasi-Kangevari, M., Abd-Rabu, R., Abidi, H., Abu-Gharbieh, E., Acuna, J. M., Adhikari, S., Advani, S. M., Afzal, M. S., Aghaie Meybodi, M., Ahinkorah, B. O., Ahmad, S., Ahmadi, A., Ahmadi, S., Ahmed, H., Ahmed, L. A., Ahmed, M. B., Al Hamad, H.,

Alahdab, F., … Zoladl, M. (2022). Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Gastroenterology and Hepatology, 7(7). https://doi.org/10.1016/S2468-1253(22)00044-9

Song, M., & Chan, A. T. (2018). The potential role of exercise and nutrition in harnessing the immune system to improve colorectal cancer survival. Gastroenterology, 155(3), 596–600. https://doi.org/10.1053/j.gastro.2018.07.038

Sumarpo, A., Martioso, P. S., & Fenny, F. (2024). Kajian Pustaka: Metode Identifikasi Penanda Biologis Feses pada Kanker Kolorektal. Jurnal Ilmu Kedokteran Dan Kesehatan, 11(1), 204–209. https://doi.org/10.33024/jikk.v11i1.13265

Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3). https://doi.org/10.3322/caac.21660

Valiati, B., Perez, R. O., & Kotze, P. G. (2020). Education levels and survival in colorectal cancer: is there really an obvious association? Intestinal Research, 18(3), 247–248.

https://doi.org/10.5217/ir.2020.00064

Ye, P., Xi, Y., Huang, Z., & Xu, P. (2020). Linking obesity with colorectal cancer: Epidemiology and mechanistic insights. Cancers, 12(6). https://doi.org/10.3390/cancers12061408

Yuan, C., Wang, C., Wu, W., Ho, C., & Chen, W. (2021). Risk factors for return to work in colorectal cancer survivors. Cancer Medicine, 10(12), 3938–3951. https://doi.org/10.1002/cam4.3952

Zhang, Q., Wang, Y., Hu, H., Huang, R., Xie, L., Liu, E., Chen, Y.-G., Wang, G., & Wang, X. (2017). Impact of socioeconomic status on survival of colorectal cancer patients. Oncotarget, 8(62), 106121–106131. https://doi.org/10.18632/oncotarget.20859




DOI: https://doi.org/10.33024/jikk.v12i2.17987

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