Fraksi Ejeksi Ventrikel Kiri dan Mortalitas Pasien IMA-EST di Rumah Sakit Umum Daerah Abdul Moeloek Provinsi Lampung
Sari
Data spesifik mengenai angka mortalitas IMA-EST di Bandar Lampung belum tersedia, proyeksi dari Institute of Health Metrics and Evaluation menunjukkan adanya peningkatan yang signifikan hingga tahun 2030. Studi ini mendalami hubungan antara fraksi ejeksi ventrikel kiri dan tingkat mortalitas pada pasien yang mengalami infark miokard akut dengan elevasi segmen ST (IMA-EST) di RSUD Abdul Moeloek, Bandar Lampung, selama periode 2021 hingga 2023. Penelitian ini menggunakan desain observasional kuantitatif dengan pendekatan retrospektif kohort, memanfaatkan data rekam medis pasien IMA-EST. Sejumlah 98 Pasien didapat dan dibagi menjadi dua kelompok: FE rendah (≤40%) dan FE Normal (>40%). Hasil analisis chi-square menunjukkan p-value 0,001 dan relative risk (RR) sebesar 5,71 yang menunjukkan adanya hubungan signifikan dengan risiko kematian yang 5,71 kali lebih tinggi pada kelompok FE rendah. Secara keseluruhan, angka mortalitas tercatat sebesar 36,8%, dengan kelompok FE rendah mencapai 60,7% dan kelompok FE normal sebesar 10,6%. Temuan ini menegaskan bahwa pasien IMA-EST dengan FE rendah memiliki risiko kematian yang jauh lebih tinggi dibandingkan dengan kelompok lainnya, sehingga fraksi ejeksi dapat dianggap sebagai prediktor prognosis yang kuat dalam konteks IMA-EST.
Kata Kunci
Teks Lengkap:
PDFReferensi
Altmann, D.R. et al. (2020) ‘Prevalence of severely impaired left ventricular ejection fraction after reperfused ST-elevation myocardial infarction’, Swiss Medical Weekly, 143. Available at: https://doi.org/10.4414/smw.2013.13869.
van der Bijl, P. et al. (2020) ‘Left Ventricular Post-Infarct Remodeling: Implications for Systolic Function Improvement and Outcomes in the Modern Era’, JACC: Heart Failure, 8(2), pp. 131–140. Available at: https://doi.org/10.1016/j.jchf.2019.08.014.
Braunwald, E. (2019) Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, Eleventh Edition. 11th edn. Philadelphia: Elsevier.
Di Cesare, M. et al. (2024) ‘The Heart of the World’, Global Heart, 19(1). Available at: https://doi.org/10.5334/gh.1288.
Demirkiran, A. et al. (2022) ‘The Dynamic Relationship between Invasive Microvascular Function and Microvascular Injury Indicators, and Their Association with Left Ventricular Function and Infarct Size at 1-Month after Reperfused ST-Segment-Elevation Myocardial Infarction’, Circulation: Cardiovascular Interventions, 15(11), pp.
–902. Available at:
https://doi.org/10.1161/Circinterventions.122.012081.
El Farissi, M. et al. (2021) ‘Hypothermia for Reduction of Myocardial Reperfusion Injury in Acute Myocardial Infarction: Closing the Translational Gap’, Circulation: Cardiovascular Interventions. Lippincott Williams and Wilkins, p. E010326. Available at: https://doi.org/10.1161/Circinterventions.120.010326.
Ferreira, J. et al. (2021) Heart Failure-Chronic Heart Failure, Pathophysiology and Mechanisms, Heart Failure with Mid-Range Ejection Fraction (HFmrEF) 803 STEMI with mid-range ejection fraction: a group of intermediate risk not to be forgotten. Available at: https://academic.oup.com/eurheartj/article/42/Supplement_1/ehab724.0803/6393539.
Hendrickson, M.J. et al. (2022) ‘Prevalence and prognostic implications of reduced left ventricular ejection fraction among patients with STEMI in India’, ESC Heart Failure, 9(6), pp. 3836–3845. Available at: https://doi.org/10.1002/ehf2.14055.
Heusch, G. (2021) ‘Myocardial stunning and hibernation revisited’, Nature Reviews Cardiology. Nature Research, pp. 522–536. Available at: https://doi.org/10.1038/s41569-021-00506-7.
Jing, Y. et al. (2023) ‘Influencing factors and prognostic value of left ventricular systolic dysfunction in patients with complete occlusion of the left anterior descending artery reperfused by primary percutaneous coronary intervention’. Available at: https://doi.org/10.21203/rs.3.rs-2454556/v1.
Lazar, M. et al. (2023) ‘Predictive factors of left ventricular ejection fraction improvement after myocardial infarction treated invasively’, Postepy w Kardiologii Interwencyjnej, 19(3), pp. 225–232. Available at: https://doi.org/10.5114/aic.2023.131475.
Leboube, S. et al. (2023) ‘What underlies sex differences in heart failure onset within the first year after a first myocardial infarction?’, Frontiers in Cardiovascular Medicine, 10. Available at: https://doi.org/10.3389/fcvm.2023.1290375.
Lei, Z. et al. (2022) ‘Predictors and prognostic impact of left ventricular ejection fraction trajectories in patients with ST-segment elevation myocardial infarction’, Aging Clinical and Experimental Research, 34(6), pp. 1429–1438. Available at: https://doi.org/10.1007/s40520-022-02087-y.
Liu, C. et al. (2023) ‘Incidence and predictors of left ventricular function change following ST-segment elevation myocardial infarction’, Frontiers in Cardiovascular Medicine, 10. Available at: https://doi.org/10.3389/fcvm.2023.1079647.
Loscalzo, J. (2019) Harrison’s Cardiovascular Medicine. 3rd edn. The McGraw-Hill Companies, Inc. .
Mensah, G.A. et al. (2023) ‘Global Burden of Cardiovascular Diseases and Risks, 1990-2022’, Journal of the American College of Cardiology, 82(25), pp. 2350–2473. Available at: https://doi.org/10.1016/j.jacc.2023.11.007.
Netter, F.H. (2019) Netter’s Cardiology. 3rd edn. Edited by G.A. Stouffer. Philadelphia: Elsevier. Available at: https://t.me/MBS_MedicalBooksStore.
Oh, S. et al. (2022) ‘Predictors for the Recovery of Left Ventricular Ejection Fraction in Myocardial Infarction’, Journal of Cardiovascular Intervention, 1(3), p. 101. Available at:
https://doi.org/10.54912/jci.2022.0007.
Perelshtein Brezinov, O. et al. (2017) ‘Prognostic value of ejection fraction in patients admitted with acute coronary syndrome: A real world study’, Medicine (United States), 96(9). Available at: https://doi.org/10.1097/MD.0000000000006226.
Ryan, M.J. and Perera, D. (2018) ‘Identifying and Managing Hibernating Myocardium: What’s New and What Remains Unknown?’, Current Heart Failure Reports, 15(4), pp. 214–223. Available at: https://doi.org/10.1007/s11897-018-0396-6.
Saklecha, A. et al. (2022) ‘Is Indexed Left Atrial Volume (LAVi) in Indian Patients with Acute Coronary Syndrome (ACS) undergoing revascularization a predictor of cardiovascular outcomes?’, Annals of Cardiac Anaesthesia, 25(1), pp. 19–25. Available at: https://doi.org/10.4103/aca.ACA_129_20.
Shmueli, H. et al. (2024) ‘Echocardiographic Predictors of Improvement of Left Ventricular Ejection Fraction below 35% in Patients with ST-Segment Elevation Myocardial Infarction’, Journal of Clinical Medicine, 13(14). Available at:
https://doi.org/10.3390/jcm13144016.
Stetsiuk, L.R. et al. (2023) ‘Features of Occurrence Ischemic Mitral Regurgitation in Patients With Acute Myocardial Infarction’, Azerbaijan Medical Journal, (4), pp. 68–74. Available at:
https://doi.org/10.34921/amj.2023.4.010.
Sundermeyer, J. et al. (2024) ‘Association between left ventricular ejection fraction, mortality and use of mechanical circulatory support in patients with non-ischaemic cardiogenic shock’, Clinical Research in Cardiology, 113(4), pp. 570–580. Available at: https://doi.org/10.1007/s00392-023-02332-y.
Turen, S and Turen, Sev (2023) ‘Gender differences in early complications after STEMI and their associations with anxiety and depression’, European Review for Medical and Pharmacological Sciences, 27, pp. 2936–2945.
Yildiz, I. et al. (2022) ‘Predictors of left ventricular ejection function decline in young patients with ST-segment elevation myocardial infarction’, Revista da Associacao Medica Brasileira, 68(6), pp. 802–807. Available at: https://doi.org/10.1590/1806-9282.20220033.
DOI: https://doi.org/10.33024/jikk.v12i3.18960
Refbacks
- Saat ini tidak ada refbacks.
##submission.copyrightStatement##
##submission.license.cc.by-nc4.footer##
Pendidikan Dokter Universitas Malahayati Lampung

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.