Length of Stay pada Pasien Infark Miokard Akut Tipe Stemi setelah Menjalani Percutaneous Coronary Intervention : a Narrative Review

Firman Sugiharto, Azalia Melati Putri, Aan Nuraeni, Henny Yulianita

Sari


ABSTRACT

 

Cardiovascular disease especially ST segment elevation (STEMI) is still a major health problem with high morbidity and mortality rates. Although recent advances in the treatment of STEMI patients have yielded better results, the need for intensive care of patients with a prolonged length of stay (LOS) can increase the burden of health care costs. An understanding of the description of LOS in STEMI patients and the factors that influence it as an effort to improve the quality of care and shorten LOS. To describe length of stay (LOS) in acute myocardial infarction patients with STEMI after treatment percutaneous coronary intervention.This study used narrative review design. The databases used were Pubmed, Ebscohost, Scopus, Taylor and Francis, and Google Scholar. The strategy for searching articles using the PCC framework with the keywords namely “Adults”, “Length of Stay”, “Percutaneous Coronary Intervention” and “Myocardial Infarction”. The results showed that 20 articles were analyzed and most of the articles said that the shortest LOS in STEMI patients after PCI was only 5.9 hours, while the longest LOS was 14 days. Most of the articles said that the LOS in STEMI patients after PCI was prolonged. Many factors affect the duration of LOS in STEMI patients, namely age, gender, complications (bleeding), history of comorbidities (diabetes mellitus, hypertension, and kidney failure), and disease severity are the predictors most experienced by STEMI patients.

 

Keywords: Length of Stay, Myocardial Infarct, STEMI

 

 

ABSTRAK

 

Penyakit kardiovaskular khususnya STEMI masih menjadi permasalahan kesehatan utama dengan tingkat morbiditas dan mortalitas yang tinggi. Meskipun kemajuan terbaru dalam penanganan STEMI telah memberikan hasil yang lebih baik, kebutuhan perawatan intensif pasien dengan durasi length of stay (LOS) yang memanjang dapat meningkatan beban biaya perawatan kesehatan. Pemahaman mengenai gambaran LOS pasien STEMI serta faktor yang mempengaruhinya penting diketahui sebagai upaya untuk meningkatkan kualitas perawatan dan mempersingkat LOS. Untuk mendeskripsikan LOS atau lama rawat Pasien Infark miokard dengan STEMI setelah percutaneous coronary intervention. Penelitian ini menggunakan desain narrative review. Basis data yang digunakan meliputi Pubmed, EBSCO-host, Scopus, Taylor and Francis, dan Google Scholar. Strategi pencarian artikel menggunakan kerangka kerja PCC dengan kata kunci “Adults”, “Length of Stay”, “Percutaneous Coronary Intervention” and “Myocardial Infarction”.  Hasil penelitian menunjukkan, dari 20 artikel yang dianalisis, sebagian besar artikel menyebutkan bahwa LOS terpendek pada pasien STEMI pasca PCI hanya 5,9 jam, sedangkan LOS terlama adalah 14 hari. Sebagian besar artikel mengatakan LOS pada pasien STEMI setelah PCI memanjang. Banyak faktor yang mempengaruhi lama LOS pada pasien STEMI yaitu usia, jenis kelamin, komplikasi (perdarahan), riwayat penyakit penyerta (diabetes melitus, hipertensi, dan gagal ginjal), dan tingkat keparahan penyakit merupakan prediktor yang paling banyak dialami oleh pasien STEMI.

 

Kata Kunci: Lama Rawat, Infark Miokardial, STEMI


Kata Kunci


Length of Stay, Myocardial Infarct, STEMI

Teks Lengkap:

Download Artikel

Referensi


Aggarwal, G., Patlolla, S. H., Aggarwal, S., Cheungpasitporn, W., Doshi, R., Sundaragiri, P. R., Rabinstein, A. A., Jaffe, A. S., Barsness, G. W., Cohen, M., & Vallabhajosyula, S. (2021). Temporal trends, predictors, and outcomes of acute ischemic stroke in acute myocardial infarction in the United States. Journal of the American Heart Association, 10(2), 1–18. https://doi.org/10.1161/JAHA.120.017693

Alqahtani, F., Balla, S., AlHajji, M., Chaudhary, F., Albeiruti, R., Kawsara, A., & Alkhouli, M. (2020). Temporal trends in the utilization and outcomes of percutaneous coronary interventions in patients with liver cirrhosis. Catheterization and Cardiovascular Interventions, 96(4), 802–810. https://doi.org/10.1002/ccd.28593

Arefian, H., Hagel, S., Fischer, D., Scherag, A., Brunkhorst, F. M., Maschmann, J., & Hartmann, M. (2019). Estimating extra length of stay due to healthcare-associated infections before and after implementation of a hospital-wide infection control program. PLoS One, 14(5), e0217159.

Azzalini, L., Solé, E., Sans, J., Vila, M., Durán, A., Gil-Alonso, D., Santaló, M., Garcia-Moll, X., & Sionis, A. (2015). Feasibility and safety of an early discharge strategy after low-risk acute myocardial infarction treated with primary percutaneous coronary intervention: The EDAMI pilot trial. Cardiology (Switzerland), 130(2), 120–129. https://doi.org/10.1159/000368890

Badgal, A. (2015). Factors affecting the average length of stay of the patients in the inpatient department in a tertiary care centre in North India. Journal of Evolution of Medical and Dental Sciences, 4(2), 150–156.

Baek, H., Cho, M., Kim, S., Hwang, H., Song, M., & Yoo, S. (2018). Analysis of length of hospital stay using electronic health records: A statistical and data mining approach. PloS One, 13(4), e0195901.

Bhat, A. G., Singh, M., Patlolla, S. H., Belford, P. M., Zhao, D. X., & Vallabhajosyula, S. (2022). Hospitalization Duration for Acute Myocardial Infarction: A Temporal Analysis of 18-Year United States Data. Medicina (Kaunas, Lithuania), 58(12). https://doi.org/10.3390/medicina58121846

Bilal, M., Samuel, R., Khalil, M. K., Singh, S., Parupudi, S., & Abougergi, M. S. (2020a). Nonvariceal upper GI hemorrhage after percutaneous coronary intervention for acute myocardial infarction: a national analysis over 11 months. Gastrointestinal Endoscopy, 92(1), 65-74.e2. https://doi.org/10.1016/j.gie.2020.01.039

Bilal, M., Samuel, R., Khalil, M. K., Singh, S., Parupudi, S., & Abougergi, M. S. (2020b). Nonvariceal upper GI hemorrhage after percutaneous coronary intervention for acute myocardial infarction: a national analysis over 11 months. Gastrointestinal Endoscopy, 92(1), 65-74.e2. https://doi.org/10.1016/j.gie.2020.01.039

Buttigieg, S. C., Abela, L., & Pace, A. (2018). Variables affecting hospital length of stay: a scoping review. Journal of Health Organization and Management.

Chehab, O., Abdallah, N., Kanj, A., Pahuja, M., Adegbala, O., Morsi, R. Z., Mishra, T., Afonso, L., & Abidov, A. (2020). Impact of immune thrombocytopenic purpura on clinical outcomes in patients with acute myocardial infarction. Clinical Cardiology, 43(1), 50–59. https://doi.org/10.1002/clc.23287

Fox, C. S., Muntner, P., Chen, A. Y., Karen, P., Roe, M. T., Cannon, C. P., Saucedo, J. F., Kontos, M. C., & Wiviott, S. D. (2018). Predicting Length of Stay and the Need for Post Acute Care after Acute Myocardial Infarction to Improve Healthcare Efficiency: A Report from the National Cardiovascular Data Registry’s ACTION Registry. 9(11), 357–365. https://doi.org/10.1161/CIRCOUTCOMES.118.004635.Predicting

Fu, K.-L., Fan, G.-Q., Han, L., Wang, X.-Z., Wang, J., Wang, Y.-S., Zhong, M., Zhang, Y., Zhang, W., & Wang, Z.-H. (2014). Impact of type 2 diabetes mellitus on hospitalization costs in older patients with acute myocardial infarction. Clinical Interventions in Aging, 9, 711–718. https://doi.org/10.2147/CIA.S59802

Granger, C. B., Bates, E. R., Jollis, J. G., Antman, E. M., Nichol, G., O’Connor, R. E., Gregory, T., Roettig, M. L., Peng, S. A., & Ellrodt, G. (2019). Improving care of STEMI in the United States 2008 to 2012: a report from the American Heart Association Mission: Lifeline program. Journal of the American Heart Association, 8(1), e008096.

Isik, T., Ayhan, E., Uluganyan, M., Gunaydin, Z. Y., & Uyarel, H. (2016). Predictors of Prolonged In-Hospital Stay after Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction. Angiology, 67(8), 756–761. https://doi.org/10.1177/0003319715617075

Jang, S.-J., Yeo, I., Feldman, D. N., Cheung, J. W., Minutello, R. M., Singh, H. S., Bergman, G., Wong, S. C., & Kim, L. K. (2020). Associations Between Hospital Length of Stay, 30-Day Readmission, and Costs in ST-Segment-Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention: A Nationwide Readmissions Database Analysis. Journal of the American Heart Association, 9(11), e015503. https://doi.org/10.1161/JAHA.119.015503

Jayaraj, J. C., Davatyan, K., Subramanian, S. S., & Priya, J. (2019). Epidemiology of myocardial infarction. Myocard. Infarct, 3(10).

Jencks, S. F. (2011). Rehospitalizations among patients in the medicare fee-for-service program. New England Journal of Medicine, 364(16), 1582.

Karamasis, G. V., Russhard, P., Al Janabi, F., Parker, M., Davies, J. R., Keeble, T. R., & Clesham, G. J. (2018). Peri-procedural ST segment resolution during Primary Percutaneous Coronary Intervention (PPCI) for acute myocardial infarction: predictors and clinical consequences. Journal of Electrocardiology, 51(2), 224–229. https://doi.org/10.1016/j.jelectrocard.2017.09.011

Kemenkes RI. (2014). Situasi kesehatan jantung. Pusat Data Dan Informasi Kementerian Kesehatan RI. https://doi.org/https://doi.org/10.1017/CBO9781107 415324.004

Kemenkes RI. (2017). Sistem informasi kesehatan II statistik pelayanan kesehatan.

Khalista, S. N., Magdaleni, A. R., & Asmoro, D. P. (2020). Hubungan kadar troponin T dengan lama perawatan dan mortalitas selama perawatan pada pasien infark miokard akut di RSUD Abdul Wahab Sjahranie Samarinda. Jurnal Sains Dan Kesehatan, 2(4), 432–437.

Khera, S., Kolte, D., Aronow, W. S., Palaniswamy, C., Mujib, M., Ahmed, A., Chugh, S. S., Balasubramaniyam, N., Edupuganti, M., Frishman, W. H., & Fonarow, G. C. (2013). Trends in acute kidney injury and outcomes after early percutaneous coronary intervention in patients ≥75 years of age with acute myocardial infarction. American Journal of Cardiology, 112(9), 1279–1286. https://doi.org/10.1016/j.amjcard.2013.06.008

Kim, L. K., Yeo, I., Cheung, J. W., Swaminathan, R. V, Wong, S. C., Charitakis, K., Adejumo, O., Chae, J., Minutello, R. M., & Bergman, G. (2018). Thirty‐Day readmission rates, timing, causes, and costs after ST‐Segment–Elevation myocardial infarction in the United States: a national readmission database analysis 2010–2014. Journal of the American Heart Association, 7(18), e009863.

Kiss, N., Hiesmayr, M., Sulz, I., Bauer, P., Heinze, G., Mouhieddine, M., Schuh, C., Tarantino, S., & Simon, J. (2021). Predicting Hospital Length of Stay at Admission Using Global and Country-Specific Competing Risk Analysis of Structural, Patient, and Nutrition-Related Data from nutritionDay 2007-2015. Nutrients, 13(11). https://doi.org/10.3390/nu13114111

Kotwal, S., Ranasinghe, I., Brieger, D., Clayton, P. A., Cass, A., & Gallagher, M. (2017). The influence of chronic kidney disease and age on revascularization rates and outcomes in acute myocardial infarction - a cohort study. European Heart Journal. Acute Cardiovascular Care, 6(4), 291–298. https://doi.org/10.1177/2048872616640995

Li, S., Zhang, X.-H., Zhou, G.-D., & Wang, J.-F. (2019). Delirium after primary percutaneous coronary intervention in aged individuals with acute ST-segment elevation myocardial infarction: A retrospective study. Experimental & Therapeutic Medicine, 17(5), 3807–3813. https://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=135931245&site=ehost-live

Lindholm, M., Hargraves, J. L., Ferguson, W. J., & Reed, G. (2012). Professional language interpretation and inpatient length of stay and readmission rates. Journal of General Internal Medicine, 27(10), 1294–1299.

Loudon, B. L., Gollop, N. D., Carter, P. R., Uppal, H., Chandran, S., & Potluri, R. (2016). Impact of cardiovascular risk factors and disease on length of stay and mortality in patients with acute coronary syndromes. International Journal of Cardiology, 220, 745–749.

Lv, J., Zhao, Q., Yang, J., Gao, X., Zhang, X., Ye, Y., Dong, Q., Fu, R., Sun, H., Yan, X., Li, W., Yang, Y., & Xu, H. (2021). Length of Stay and Short-Term Outcomes in Patients with ST-Segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention: Insights from the China Acute Myocardial Infarction Registry. International Journal of General Medicine, 14(July), 5981–5991. https://doi.org/10.2147/IJGM.S330379

McAlister, F. A., Bakal, J. A., Majumdar, S. R., Dean, S., Padwal, R. S., Kassam, N., Bacchus, M., & Colbourne, A. (2014). Safely and effectively reducing inpatient length of stay: a controlled study of the General Internal Medicine Care Transformation Initiative. BMJ Quality & Safety, 23(6), 446–456.

Mechanic, O. J., Gavin, M., & Grossman, S. A. (2022). Acute Myocardial Infarction. StatPearls [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK459269/

Melberg, T., Jørgensen, M., Ørn, S., Solli, T., Edland, U., & Dickstein, K. (2015). Safety and health status following early discharge in patients with acute myocardial infarction treated with primary PCI: A randomized trial. European Journal of Preventive Cardiology, 22(11), 1427–1434. https://doi.org/10.1177/2047487314559276

Mirbolouk et al. (2020). The factors related to hospitalization period in patients with acute myocardial infarction treated after primary percutaneous coronary intervention. ARYA Atherosclerosis, 16(3), 115–122. https://doi.org/10.22122/arya.v16i3.1915

Mirbolouk, F., Salari, A., Gholipour, M., Nikfarjam, S., Pourbahador, R., Mohamadnia, H., & Akbari-Parsa, N. (2020). The factors related to hospitalization period in patients with acute myocardial infarction treated after primary percutaneous coronary intervention. ARYA Atherosclerosis, 16(3), 1–8. https://doi.org/10.22122/arya.v16i3.1915

Nguyen, B., Fennessy, M., Leya, F., Nowak, W., Ryan, M., Freeberg, S., Gill, J., Dieter, R. S., Steen, L., Lewis, B., Cichon, M., Probst, B., Jarotkiewicz, M., Wilber, D., & Lopez, J. J. (2015a). Comparison of primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction during and prior to availability of an in-house STEMI system: Early experience and intermediate outcomes of the HARRT program for achieving routin. Catheterization and Cardiovascular Interventions, 86(2), 186–196. https://doi.org/10.1002/ccd.25769

Ojha, N., & Dhamoon, A. (2021). Myocardial Infarction. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK537076/

Patel, N. J., Pau, D., Nalluri, N., Bhatt, P., Thakkar, B., Kanotra, R., Agnihotri, K., Ainani, N., Patel, N., Patel, N., Shah, S., Kadavath, S., Arora, S., Sheikh, A., Badheka, A. O., Lafferty, J., Alfonso, C., & Cohen, M. (2016). Temporal Trends, Predictors, and Outcomes of In-Hospital Gastrointestinal Bleeding Associated With Percutaneous Coronary Intervention. American Journal of Cardiology, 118(8), 1150–1157. https://doi.org/10.1016/j.amjcard.2016.07.025

Satilmisoglu, M. H., Gorgulu, S., Aksu, H. U., Aksu, H., Ertaş, G., Tasbulak, O., Buturak, A., Kalkan, A. K., Degirmencioglu, A., Koroglu, B., Tusun, E., Murat, A., & Oz, A. (2016). Safety of Early Discharge after Primary Percutaneous Coronary Intervention. American Journal of Cardiology, 117(12), 1911–1916. https://doi.org/10.1016/j.amjcard.2016.03.039

Singh, V., Mendirichaga, R., Savani, G. T., Rodriguez, A. P., Dabas, N., Munagala, A., Alfonso, C. E., Cohen, M. G., Elmariah, S., & Palacios, I. F. (2017). Coronary revascularization for acute myocardial infarction in the HIV population. Journal of Interventional Cardiology, 30(5), 405–414. https://doi.org/10.1111/joic.12433

Sugiyama, T., Hasegawa, K., Kobayashi, Y., Takahashi, O., Fukui, T., & Tsugawa, Y. (2015). Differential time trends of outcomes and costs of care for acute myocardial infarction hospitalizations by ST elevation and type of intervention in the United States, 2001–2011. Journal of the American Heart Association, 4(3), e001445.

Swaminathan, R. V, Rao, S. V, McCoy, L. A., Kim, L. K., Minutello, R. M., Wong, S. C., Yang, D. C., Saha-Chaudhuri, P., Singh, H. S., Bergman, G., & Feldman, D. N. (2015). Hospital length of stay and clinical outcomes in older STEMI patients after primary PCI: a report from the National Cardiovascular Data Registry. Journal of the American College of Cardiology, 65(12), 1161–1171. https://doi.org/10.1016/j.jacc.2015.01.028

Takaoka, N., Tsujita, K., Kaikita, K., Hokimoto, S., Mizobe, M., Nagano, M., Horio, E., Sato, K., Nakayama, N., & Yoshimura, H. (2014). Comprehensive analysis of intravascular ultrasound and angiographic morphology of culprit lesions between ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome. International Journal of Cardiology, 171(3), 423–430.

Tipton K, Leas BF, Mull NK, et al. (2021). Interventions To Decrease Hospital Length of Stay [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US). https://www.ncbi.nlm.nih.gov/books/NBK574438/

Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., & Delling, F. N. (2020). Heart disease and stroke statistics—2020 update: a report from the American Heart Association. Circulation, 141(9), e139–e596.

Weiss, A. J., & Elixhauser, A. (2014). Overview of hospital stays in the United States, 2012: statistical brief.

White-Williams, C., Shirey, M., Eagleson, R., Clarkson, S., & Bittner, V. (2021). An interprofessional collaborative practice can reduce heart failure hospital readmissions and costs in an underserved population. Journal of Cardiac Failure, 27(11), 1185–1194.

World Health Organization. (2010). The world health report: health systems financing: the path to universal coverage. World Health Organization.

Yip, W., Fu, H., Chen, A. T., Zhai, T., Jian, W., Xu, R., Pan, J., Hu, M., Zhou, Z., & Chen, Q. (2019). 10 years of health-care reform in China: progress and gaps in universal health coverage. The Lancet, 394(10204), 1192–1204.




DOI: https://doi.org/10.33024/mnj.v5i5.9737

Refbacks

  • Saat ini tidak ada refbacks.


Penerbit: Universitas Malahayati


 Creative Commons License

Semua artikel dapat digunakan dibawah lisensi Creative Commons Attribution-ShareAlike 4.0 International License