Mobilisasi Dini pada Pasien Post Kraniotomi: Systematic Review
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ABSTRACT
Craniotomy is a neurosurgical procedure associated with postoperative complications such as infection and neurological decline due to immobilization. Early mobilization may accelerate recovery; however, its safety remains controversial, particularly in critically ill patients. This review aimed to analyze existing studies to determine the optimal timing for mobilization and its outcomes. A comprehensive literature search was conducted using descriptors and keywords in databases including Scopus, PubMed, ProQuest, Web of Science, and ScienceDirect. Study appraisal was carried out using the Joanna Briggs Institute (JBI) checklist. The included studies consisted of quasi-experimental designs, randomized controlled trials (RCTs), and non-experimental studies (prospective and retrospective) published between 2016 and 2025 in English. The search yielded 1,250 articles, of which 7 met the inclusion criteria and were reviewed. Early mobilization was initiated at 6, 12, 24, and 28–72 hours postoperatively, depending on patient tolerance. The studies involved patients undergoing general craniotomy procedures, including those for chronic subdural hematoma, aneurysms, and brain tumors. Outcomes assessed included length of stay (LOS), postoperative complications, and functional recovery. The findings suggest that initiating early mobilization within the first 24 hours—particularly within 12 hours—is an optimal strategy to reduce LOS, minimize complications, and accelerate functional improvement. Early mobilization typically progressed from head elevation, to sitting in a chair, standing unassisted, and walking, based on patient tolerance.
Keywords: Early Mobilization, Post-Craniotomy.
ABSTRAK
Kraniotomi adalah prosedur bedah saraf dengan risiko komplikasi pascaoperasi seperti infeksi dan penurunan neurologis akibat imobilisasi. Mobilisasi dini dapat mempercepat pemulihan, tetapi keamanannya masih diperdebatkan, terutama pada pasien kritis. Review ini menganalisis studi-studi untuk menentukan waktu optimal mobilisasi dan dampaknya. Pencarian literatur dilakukan secara komprehensif menggunakan deskriptor dan kata kunci pada database Scopus, PubMed, Proquest, Web Of Science dan ScienceDirect. Appraisal studi menggunakan checklistdari Joanna Briggs Institute (JBI). Desain studi artikel yang disertakan meliputi quasy eksperiment, Randomized Control Trial (RCT), serta non eksperiemental study (prospektif dan studi retrospektif) yang diterbitkan pada tahun 2016-2025 dalam Bahasa Inggris. Pencarian menghasilkan sebanyak 1250 artikel, dan 7 artikel ditelaah dalam review ini. Mobilisasi dini dilakukan saat 6 jam pascaoperasi, 12 jam pascaoperasi, 24 jam pascaoperasi, dan 28-72 jam pascaoperasi sesuai dengan toleransi pasien. Karakteristik pasien yang terdapat pada artikel mencakup pasien yang menjalani kraniotomi umum termasuk untuk chronic subdural hematoma, aneurisma, dan tumor otak. Penelitian-penelitian tersebut juga mengobservasi length of stay (LOS), komplikasi postoperasi, dan fungsional. Hasil menunjukkan bahwa inisiasi mobilisasi dini dalam 24 jam pertama, terutama <12 jam, merupakan strategi optimal untuk memperpendek (LOS), meminimalkan komplikasi, dan mempercepat peningkatan pemulihan fungsional. Mobilisasi dini dimulai dari elevasi kepala, kemudian duduk di kursi, berdiri tanpa bantuan, dan berjalan sesuai toleransi pasien.
Kata Kunci: Mobilisasi Dini, Post Kraniotomi.
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Al-Dorzi, H. M., Alqahtani, S., Al-Dawood, A., Al-Hameed, F. M., Burns, K. E. A., Mehta, S., Jose, J., Alsolamy, S. J., Abdukahil, S. A. I., Afesh, L. Y., Alshahrani, M. S., Mandourah, Y., Almekhlafi, G. A., Almaani, M., Al Bshabshe, A., Finfer, S., Arshad, Z., Khalid, I., Mehta, Y., … Group, For The S. C. C. T. (2023). Association Of Early Mobility With The Incidence Of Deep-Vein Thrombosis And Mortality Among Critically Ill Patients: A Post Hoc Analysis Of Prevent Trial. Critical Care, 27(1), 83. Https://Doi.Org/10.1186/S13054-023-04333-9
Aromataris, E., Lockwood, C., Porritt, K., Pilla, B., & Jordan, Z. (Eds.). (2024). Jbi Manual For Evidence Synthesis. Jbi. Https://Doi.Org/10.46658/Jbimes-24-01
Beez, T., Munoz-Bendix, C., Steiger, H.-J., & Beseoglu, K. (2019). Decompressive Craniectomy For Acute Ischemic Stroke. Critical Care, 23(1). Https://Doi.Org/10.1186/S13054-019-2490-X
Brink, H., & Van Der Walt, C. (2006). Fundamentals Of Research Methodology For Health Care Professionals. Juta.
Elayat, A., Jena, S. S., Nayak, S., Sahu, R. N., & Tripathy, S. (2021). “Enhanced Recovery After Surgery – Eras In Elective Craniotomies-A Non-Randomized Controlled Trial.” Bmc Neurology, 21(1), 1–17. Https://Doi.Org/10.1186/S12883-021-02150-7
Foudhaili, A., Barthélémy, R., Collet, M., De Roquetaillade, C., Kerever, S., Vitiello, D., Mebazaa, A., & Chousterman, B. G. (2023). Impact Of Early Out-Of-Bed Mobilization On Functional Outcome In Patients With Aneurysmal Subarachnoid Hemorrhage: A Retrospective Cohort Study. World Neurosurgery, 175, E278–E287. Https://Doi.Org/10.1016/J.Wneu.2023.03.073
Foudhaili, A., Vitiello, D., & Chosuterman, B. G. (2024). Early Mobilization Of Patients With Subarachnoid Haemorrhage: A National Survey Of French Intensive Care Units. Journal Of Rehabilitation Medicine, 56, Jrm17734. Https://Doi.Org/10.2340/Jrm.V56.17734
Fuest, K., & Schaller, S. J. (2019). Early Mobilisation On The Intensive Care Unit: What We Know | Frühmobilisation Auf Der Intensivstation: Wie Ist Die Evidenz? Medizinische Klinik - Intensivmedizin Und Notfallmedizin, 114(8), 759–764. Https://Doi.Org/10.1007/S00063-019-0605-4
González-Darder, J. M. (2016). History Of The Craniotomy | Historia De La Craneotomía. Neurocirugia, 27(5), 245–257. Https://Doi.Org/10.1016/J.Neucir.2016.02.002
Haddaway, N. R., Page, M. J., Pritchard, C. C., & Mcguinness, L. A. (2022). Prisma2020: An R Package And Shiny App For Producing Prisma 2020-Compliant Flow Diagrams, With Interactivity For Optimised Digital Transparency And Open Synthesis. Campbell Systematic Reviews, 18(2), E1230. Https://Doi.Org/Https://Doi.Org/10.1002/Cl2.1230
Kaewborisutsakul, A., Kitsiripant, C., Kaewsridam, S., Kaewborisutsakul, W. K., & Churuangsuk, C. (2023). The Influence Of Enhanced Recovery After Surgery Protocol Adherence In Patients Undergoing Elective Neuro-Oncological Craniotomies. World Neurosurgery: X, 19(August 2022), 100196. Https://Doi.Org/10.1016/J.Wnsx.2023.100196
Karic, T., Røe, C., Nordenmark, T. H., Becker, F., Sorteberg, W., & Sorteberg, A. (2017). Effect Of Early Mobilization And Rehabilitation On Complications In Aneurysmal Subarachnoid Hemorrhage. Journal Of Neurosurgery, 126(2), 518–526. Https://Doi.Org/10.3171/2015.12.Jns151744
Maties, O., & Gelb, A. W. (2022). Is There A Best Technique In The Patient With Increased Intracranial Pressure? In Evidence-Based Practice Of Anesthesiology. Https://Doi.Org/10.1016/B978-0-323-77846-6.00042-2
Nobles, K., Cunningham, K., Fecondo, B., Closs, S. M., Donovan, K., & Kumar, M. A. (2024). Mobilization In Neurocritical Care: Challenges And Opportunities. Current Neurology And Neuroscience Reports, 25(1), 13. Https://Doi.Org/10.1007/S11910-024-01399-Y
Pinto, V., Sousa, S. A., Da Silva, F. V., Da Costa, T. R., Fernandes, A. P., Batata, R., Noronha, C., Silva, J. M., Ferreira, S., Sobral, S., Alves, C., Rangel, R., Calheiros, A., Antunes, J., Fidalgo, M., Grande, A., Figueiredo, G., Rocha, L., Cunha, E., … Oliveira, T. (2024). Get-Up Trial 1-Year Results: Long-Term Impact Of An Early Mobilization Protocol On Functional Performance After Surgery For Chronic Subdural Hematoma. Journal Of Neurosurgery, 140(5), 1434–1441. Https://Doi.Org/10.3171/2023.8.Jns231509
Rizk, A. A., Nijs, K., Di Donato, A. T., Hasanaly, N., Masohood, N. S., & Chowdhury, T. (2025). Epidemiology Of Post-Craniotomy Hypertension And Its Association With Adverse Outcome(S): A Systematic Review And Meta-Analysis. Journal Of Neurosurgical Anesthesiology. Https://Doi.Org/10.1097/Ana.0000000000001025
Staartjes, V. E., Spinello, A., Schwendinger, N., Germans, M. R., Serra, C., & Regli, L. (2024). Safety And Effectiveness Of An Enhanced Recovery Protocol In Patients Undergoing Burr Hole Evacuation For Chronic Subdural Hematoma. Neurosurgery, 95(1), 146–157. Https://Doi.Org/10.1227/Neu.0000000000002849
Sun, M. Z., Babayan, D., Chen, J.-S., Wang, M. M., Naik, P. K., Reitz, K., Li, J. J., Pouratian, N., & Kim, W. (2021). Postoperative Admission Of Adult Craniotomy Patients To The Neuroscience Ward Reduces Length Of Stay And Cost. Neurosurgery, 89(1), 85–93. Https://Doi.Org/10.1093/Neuros/Nyab089
Wang, L., Cai, H., Wang, Y., Liu, J., Chen, T., Liu, J., Huang, J., Guo, Q., & Zou, W. (2022). Enhanced Recovery After Elective Craniotomy: A Randomized Controlled Trial. Journal Of Clinical Anesthesia, 76(November 2021), 110575. Https://Doi.Org/10.1016/J.Jclinane.2021.110575
Yataco, R. A., Arnold, S. M., Brown, S. M., David Freeman, W., Carmen Cononie, C., Heckman, M. G., Partridge, L. W., Stucky, C. M., Mellon, L. N., Birst, J. L., Zapata-Cooper, M. H., & Schudlich, D. M. (2019). Early Progressive Mobilization Of Patients With External Ventricular Drains: Safety And Feasibility. Neurocritical Care, 30(2), 414–420. Https://Doi.Org/10.1007/S12028-018-0632-7
Zhu, S., Hu, C., Gong, L., & Xie, J. (2022). Clinical Analysis Of Hospitalized Patients With Distal Deep Venous Thrombosis | 住院患者远端深静脉血栓形成的临床分析. Chinese Journal Of General Practitioners, 21(6), 554–559. Https://Doi.Org/10.3760/Cma.J.Cn114798-20220127-00062
DOI: https://doi.org/10.33024/mahesa.v6i2.20624
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