Primary Raynaud’s Disease in a Young Adult: A Case Report
Sari
ABSTRACT
Raynaud’s phenomenon (RP) is characterized by intermittent vasospasm and subsequent ischemia of the extremities, typically triggered by cold exposure or emotional stress. This leads to a distinct triphasic discoloration of the fingers or toes, progressing from pallor to hyperemia. This case report describes a 20-year-old woman presenting with a 1-year history of episodic bilateral finger discoloration (pallor, cyanosis, erythema) triggered by cold exposure, consistent with primary Raynaud's phenomenon. Physical examination revealed no digital ulcers or skin changes, and basic laboratory tests were unremarkable, though autoimmune serology was unavailable due to resource limitations. The patient's photograph documenting an acute attack provided valuable diagnostic support. Management emphasized conservative measures including cold avoidance and behavioral modifications, which successfully controlled symptoms. This case highlights the clinical diagnosis of primary RP in resource-constrained settings, the utility of patient-documented evidence, and the effectiveness of non-pharmacological approaches.
Keywords: Ischemia, Raynaud phenomenon, Vasospasm.
Teks Lengkap:
Download Artikel (English)Referensi
Besag, F. M., Vasey, M. J., Roy, S., & Cortese, S. (2025). Raynaud Syndrome Associated with Medication for Attention-Deficit/Hyperactivity Disorder: A Systematic Review. CNS drugs, 39(3), 213-241.
Castanedo, L. Q., Rodríguez, M. F., Rodríguez, D. N., Pedrero, R. M., Fernández, C. C., & de Lucas Laguna, R. (2021). Botulinum toxin a treatment for primary and secondary Raynaud's phenomenon in teenagers. Dermatologic Surgery, 47(1), 61-64.
Choi, E., & Henkin, S. (2021). Raynaud’s phenomenon and related vasospastic disorders. Vascular Medicine, 26(1), 56–70. https://doi.org/10.1177/1358863X20983455
Garner, R., Kumari, R., Lanyon, P., Doherty, M., & Zhang, W. (2015). Prevalence, risk factors and associations of primary Raynaud’s phenomenon: systematic review and meta-analysis of observational studies. BMJ Open, 5(3), e006389. https://doi.org/10.1136/bmjopen-2014-006389
Goundry, B., Bell, L., Langtree, M., & Moorthy, A. (2012). Diagnosis and management of Raynaud’s phenomenon. BMJ, 344(feb07 1), e289–e289. https://doi.org/10.1136/bmj.e289
Herrick, A. L. (2017). Evidence-based management of Raynaud’s phenomenon. Therapeutic Advances in Musculoskeletal Disease, 9(12), 317–329. https://doi.org/10.1177/1759720X17740074
Jones, G. T., Herrick, A. L., Woodham, S. E., Baildam, E. M., Macfarlane, G. J., & Silman, A. J. (2003). Occurrence of Raynaud's phenomenon in children ages 12–15 years: prevalence and association with other common symptoms. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology, 48(12), 3518-3521.
Kwakkenbos, L., Nassar, E.-L., Sigmans, N., & Thombs, B. D. (2024). Non-drug Approaches to Treating Raynaud’s Phenomenon. In Raynaud’s Phenomenon (pp. 325–341). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-52581-0_18
Lambova, S. N., & Müller-Ladner, U. (2009). The role of capillaroscopy in differentiation of primary and secondary Raynaud’s phenomenon in rheumatic diseases: a review of the literature and two case reports. Rheumatology international, 29(11), 1263-1271.
Musa, R., & Qurie, A. (2025). Raynaud Disease.
Nawaz, I., Nawaz, Y., Nawaz, E., Manan, M. R., & Mahmood, A. (2022). Raynaud’s Phenomenon: Reviewing the Pathophysiology and Management Strategies. Cureus. https://doi.org/10.7759/cureus.21681
Nigrovic, P. A., Fuhlbrigge, R. C., & Sundel, R. P. (2003). Raynaud’s phenomenon in children: a retrospective review of 123 patients. Pediatrics, 111(4), 715-721.
Orsini, M., da Silva Catharino, A. M., Camargo Silveira, V., Henrique Melo Reis, C., de Sant’ Anna Junior, M., & Eduardo Cardoso, C. (2021). Raynaud’s phenomenon after cold exposure: A case report. International Journal of Case Reports and Images, 12, 1. https://doi.org/10.5348/101267Z01MO2021CR
Pauling, J. D., & Matucci-Cerinic, M. (2024). Definition, Nomenclature, and Diagnostic Criteria. In Raynaud’s Phenomenon (pp. 15–23). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-52581-0_2
Pope, J. E. (2013). Raynaud's phenomenon (primary). BMJ clinical evidence, 2013, 1119.
Planchon, B., Pistorius, M. A., Beurrier, P., & De Faucal, P. (1994). Primary Raynaud's phenomenon: age of onset and pathogenesis in a prospective study of 424 patients. Angiology, 45(8), 677-686.
Sharathkumar, A. A., & Castillo-Caro, P. (2011). Primary Raynaud's phenomenon in an infant: a case report and review of literature. Pediatric Rheumatology, 9(1), 16.
Spencer-Green, G. (1998). Outcomes in primary Raynaud phenomenon: a meta-analysis of the frequency, rates, and predictors of transition to secondary diseases. Archives of internal medicine, 158(6), 595-600.
Virk, M., & Martin, L. (2025, July). Raynaud’s Phenomenon: A Rare Presentation with Gangrene. In The Journal of Rheumatology (Vol. 52, No. Suppl 2, pp. 116-117). The Journal of Rheumatology.
Temprano, K. K. (2016). A Review of Raynaud’s Disease. Missouri Medicine, 113(2), 123–126.
DOI: https://doi.org/10.33024/mahesa.v6i2.20742
Refbacks
- Saat ini tidak ada refbacks.
Publisher: Universitas Malahayati Lampung

Semua artikel dapat digunakan dibawah lisensi Creative Commons Attribution-ShareAlike 4.0 International License


Panduan Penulisan





