Gambaran Hasil Tes Cepat Molekuler (TCM) Pada Pasien Suspek TB Paru di RS Tk.II Dustira

Drajat Priyadi, Arfa Izzati

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ABSTRACT

 

Tuberculosis (TB) remains a major infectious disease and global health concern, particularly in Indonesia. The Molecular Rapid Test (TCM) plays a critical role in the early detection of tuberculosis and its resistance to rifampicin. This study aimed to describe the results of TCM testing among patients with suspected pulmonary TB at RS Tk.II Dustira. This study used a descriptive cross-sectional study design and analyzed  586 patient records obtained from the Tuberculosis Information System (SITB) and hospital medical records between January and March 2025. Data were analyzed descriptively and presented as frequency and percentage distributions. Most patients tested MTB-negative (85%), followed by MTB-rifampicin-sensitive (14%) and rifampicin-resistant (1%). The majority of patients were male (56%) and belonged to the adult age group (18-59 years; 59%). Comorbidity documentation showed a high proportion of unknown status, with 83% recorded as having an unknown Diabetes mellitus status and 89% an unknown HIV status.These findings highlight the need to improve comorbidity documentation to support more effective management of TB cases.

 

Keywords: Pulmonary TB, TCM, Comorbidity, Age, Gender.

 

ABSTRAK

 

Tuberkulosis (TB) merupakan penyakit menular yang masih menjadi masalah kesehatan global, termasuk di Indonesia. Deteksi dini menggunakan Tes Cepat Molekuler (TCM) berperan penting dalam diagnosis TB dan resistensinya terhadap rifampisin. Penelitian ini bertujuan untuk mendeskripsikan gambaran hasil pemeriksaan TCM pada pasien suspek TB Paru di RS Tk.II Dustira. Penelitian ini menggunakan desain deskriptif dengan pendekatan cross-sectional terhadap 586 pasien dari Sistem Informasi Tuberkulosis (SITB) dan rekam medis selama bulan Januari hingga Maret 2025. Analisis dilakukan secara deskriptif dan disajikan dalam bentuk distribusi frekuensi dan persentase. Mayoritas pasien menunjukkan hasil MTB negatif (85%), MTB rifampisin sensitif (14%), dan rifampisisn resisten (1%). Secara demografi, pasien mayoritas berjenis kelamin laki-laki (56%) dan kelompok usia dewasa (18-59 tahun ; 59%). Pada pencatatan status komorbid ditemukan prevalensi status tidak diketahui yang cukup tinggi dengan 83% tidak memiliki data status DM (83%) dan 89% tidak diketahui status HIV-nya. Temuan ini menekankan perlunya peningkatan pencatatan komorbiditas untuk mendukung penatalaksanaan kasus TB paru yang lebih efektif.

 

Kata Kunci: TB Paru, TCM, Komorbiditas, Usia, Jenis Kelamin.


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Referensi


Arbués, M. D., & Rossetti, M. L. R. (2024). Evaluation of the GeneXpert MTB/RIF to diagnose tuberculosis in a public health laboratory. Revista de Saude Publica, 58. https://doi.org/10.11606/s1518-8787.2024058005306

Bai, W., & Ameyaw, E. K. (2024). Global, regional and national trends in tuberculosis incidence and main risk factors: a study using data from 2000 to 2021. BMC Public Health, 24(1). https://doi.org/10.1186/s12889-023-17495-6

Biset, S., Teferi, M., Alamirew, H., Birhanu, B., Dessie, A., Aschale, A., Haymanot, A., Dejenie, S., Gebremedhin, T., Abebe, W., & Adane, G. (2024). Trends of Mycobacterium tuberculosis and Rifampicin resistance in Northwest Ethiopia: Xpert® MTB/RIF assay results from 2015 to 2021. BMC Infectious Diseases, 24(1). https://doi.org/10.1186/s12879-024-09135-0

Boadu, A. A., Yeboah-Manu, M., Osei-Wusu, S., & Yeboah-Manu, D. (2024). Tuberculosis and diabetes mellitus: The complexity of the comorbid interactions. In International Journal of Infectious Diseases (Vol. 146). Elsevier B.V. https://doi.org/10.1016/j.ijid.2024.107140

Chabaria, E., Perdani, R., & Pratiwi, W. (2024). Gambaran Hasil Pemeriksaan Tes Cepat Molekuler (TCM) Pada Pasien Suspek Tuberkulosis Paru di RSUD Ulin Banjarmasin Tahun 2023. Jurnal Mahasiswa Polanka (JMPL), 1, 220–227. https://doi.org/10.52674/jmpl.v1i2.134

Chidambaram, V., Tun, N. L., Majella, M. G., Ruelas Castillo, J., Ayeh, S. K., Kumar, A., Neupane, P., Sivakumar, R. K., Win, E. P., Abbey, E. J., Wang, S., Zimmerman, A., Blanck, J., Gupte, A., Wang, J. Y., & Karakousis, P. C. (2021). Male sex is associated with worse microbiological and clinical outcomes following tuberculosis treatment: A retrospective cohort study, a systematic review of the literature, and meta-analysis. In Clinical Infectious Diseases (Vol. 73, Issue 9, pp. 1580–1588). Oxford University Press. https://doi.org/10.1093/cid/ciab527

Kemenkes RI. (2023). Petunjuk Teknis Pemeriksaan Tuberkulosis Menggunakan Tes Cepat Molekuer geneXpert. Jakarta: Kementerian Kesehatan RI.

Kemenkes RI. (2025). Buku Panduan Tenaga Medis dan Tenaga Kesehatan Tuberkulosis. Jakarta: Kementerian Kesehatan RI.

Kumar, N. P., & Babu, S. (2023). Impact of diabetes mellitus on immunity to latent tuberculosis infection. In Frontiers in Clinical Diabetes and Healthcare (Vol. 4). Frontiers Media SA. https://doi.org/10.3389/fcdhc.2023.1095467

Kusdiantini, A., & Asty, A. (2024). Hubungan Kadar Hemoglobin dan Kadar Gula Darah Terhadap Penderita Diabetes Mellitus Tipe II. Jurnal Infokes (Informasi Kesehatan), 7(2), 97-102. https://doi.org/10.56689/infokes.v7i2.1300

Nuraini, N., Sihartono, S., & Raharjo, M. (2021). Faktor-faktor yang Mempengaruhi Kejadian Tuberkulosis: Sebuah Review. Jurnal Kesehatan Lingkungan, 13(1), 20–25. https://doi.org/10.29238/sanitasi.v13i1.1079

Putra, W. M., Wahyono, T. Y. M., & Salamah, Q. N. (2022). Keberhasilan Pengobatan dan Karakteristik Pasien Tuberkulosis Sensitif Obat (TB SO) di Provinsi DKI Jakarta. Jurnal Penelitian Kesehatan Suara Forikes, 13, 1. https://doi.org/10.33846/sf13nk401

Ralfiansha, M., Afifah, A. N., & Farsida, R. A. (2023). Gambaran Faktor-faktor Tuberkulosis Paru Pada Lansia di Wilayah Kerja Pusat Kesehatan Masyarakat Pisangan, Ciputat Timur Periode Januari 2022 - Oktober 2023. Dalam Prosiding Seminar Nasional Penelitian dan Pengabdian kepada Masyarakat (hlm. 56-53). Universitas Muhammadiyah Jakarta. http://jurnal.umj.ac.id/index.php/semnaslit

Rejito, A., Bintari, N. W. D., & Idayani, S. (2024). Hasil Pemeriksaan Tes Cepat Molekuler (GeneXpert) Pasien Suspek Tuberkulosis Paru di RSUD Kabupaten Buleleng. Jurnal Riset Kesehatan Nasional, Vol. 8(No. 2), 149–154. https://doi.org/10.37294

Rimal, R., Shrestha, D., Pyakurel, S., Poudel, R., Shrestha, P., Rai, K. R., Ghimire, G. R., Rai, G., & Rai, S. K. (2022). Diagnostic performance of GeneXpert MTB/RIF in detecting MTB in smear-negative presumptive TB patients. BMC Infectious Diseases, 22(1). https://doi.org/10.1186/s12879-022-07287-5

Setiawan, G., & Nurhayati, N. A. (2021). Gambaran Kepatuhan Pasien dalam Pengobatan TBC di Poliklinik Paru RS. Dustira Cimahi. Jurnal Health Sains, 2(2). https://doi.org/10.46799/jhs.v2i2.106

Sossen, B., Kubjane, M., & Meintjes, G. (2025). Tuberculosis and HIV coinfection: Progress and challenges towards reducing incidence and mortality. In International Journal of Infectious Diseases. Elsevier B.V. https://doi.org/10.1016/j.ijid.2025.107876

Sunarmi, & Kurniawaty. (2022). Hubungan Karakteristik Pasien TB Paru Dengan Kejadian Tuberkulosis. Jurnal ‘Aisyiyah Medika, 7(2), 182–187. https://doi.org/10.36729

Wahyuni, A. E. S., & Sudrajat, A. (2024). Gambaran Nilai SGPT Pasien Tuberkulosis Dengan Penggunaan OAT di Rumah Sakit DKH Kedungwaringin. Journal of Health Analyst Student (JHAS), 1(1), 7-11. https://journal.piksi.ac.id/index.php/jhas/article/view/1538

WHO. (2020). Global Tuberculosis Report 2020. Geneva: World Health Organization. https://www.who.int/publications/i/item/9789240013131

WHO. (2021). Global Tuberculosis Report 2021. Geneva: World Health Organization. https://www.who.int/publications/i/item/9789240037021

WHO. (2024). 2024 Global tuberculosis report. Geneva: World Health Organization. https://www.who.int/publications-detail-redirect/9789240101531

Zuleika, P., & Legiran. (2022). Cross-Sectional Study as Research Design in Medicine. Archives of The Medicine and Case Reports, 3(2), 256–259. https://doi.org/10.37275/amcr.v3i2.193




DOI: https://doi.org/10.33024/mahesa.v6i4.21813

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