UJI DAYA HAMBAT KRIM KULIT APEL MANALAGI (Malus sylvestris Mill) TERHADAP BAKTERI PROPIONIBACTERIUM ACNE PENYEBAB JERAWAT DENGAN METODE DIFUSI SUMURAN

Liana Fajriah, Robby Candra Purnama

Sari


Manalagi apple (Malus sylvestris Mill) is one type of poor apple that has been widely consumed by the people of Indonesia because it has a sweet, delicious taste, and is easy to obtain. This study aimed to test the effectiveness of the anti-acne cream of Manalagi Apple (Malus sylvestris Mill) peel extract against Propionibacterium acnes bacteria. The extract obtained by maceration using 96% ethanol solvent was made into two formulations of cream concentration, namely 5% and 10% then tested on Propionibacterium acne bacteria using MHA media. The method used is the well diffusion method. Manalagi Apple peel extract was declared to meet the requirements for a good cream preparation. The 5% cream formulation has shown an inhibitory effect on Propionibacterium acne bacteria with an average diameter of 19.72 mm (intermedied), a concentration of 10% with a value of 20.11 mm (sensitive). From the results obtained it can be concluded that the preparation of Manalagi apple peel extract cream (Malus sylvestris Mill) is effective in inhibiting the growth of Propionibacterium acne bacteria. The most effective cream is in cream preparations with an extract concentration of 10%.


Teks Lengkap:

PDF

Referensi


Chhetri,H.P., Yogol, N. S., Scherhan, J.,Anupa, K. C., Mansoor, S.,& Thapa, P.,2010. Formulation And Evaluation Of Anitimicrobial and tehnology Herbal Oinment, Journal Of Siense, Engineering And Tecnology. Clinical Laboratory Standar Institute.2014 Departemen Kesehatan Republik Indonesia. 2014. Farmakope Indonesia edisi V. Jakarta Górniak, I., Bartoszewski, R., & Króliczewski, J. (2019).

Comprehensive review of antimicrobial activities of plant flavonoids. Phytochemistry Reviews, 18(1), 241-272.

Hapsari, M. D. Y., & Estiasih, T. (2014). Variasi Proses Dan Grade Apel (Malus sylvestris Mill) Pada Pengolahan Minuman Sari Buah Apel: Kajian Pustaka [In Press Juli 2015]. Jurnal Pangan dan Agroindustri, 3(3).

Jawetz. 2015. Mikrobiologi kedokteran. Jakarta: EGC.

Octaviany, V. D., et al. 2017. Uji Efektifitas Ekstrak Kulit Apel (Malussylvestris Mill) Var. Rome Beauty Terhadap Kadar Enzim SGPT Tikus (Rattusnorvegicus) Galur Wistar Yang Diinduksi CCL4 (Karbon Tetra Klorida). Jurnal Profesi Medika, Vol.11, No.2.

Pratiwi,S.T.2008.Mikrobiologi Farmasi. Jakarta: EMS.

Putri, Nuriyanda Setia. 2020. Uji Daya Hambat Formulasi Krim Dengan Bahan Aktif Ekstrak Daun Pegagan (Centella asiatica (L)Urb) Sebagai Antijerawat Terhadap Bakteri Propionibacterium acne Dengan Metode Difusi Sumuran. KTI. Univ.Malahayati. Lampung.

PUTRI, Z. F. (2010). Uji aktivitas antibakteri ekstrak etanol daun sirih (Piper betle L.) terhadap Propionibacterium acne Dan Staphylococcus aureus multiresisten (Doctoral dissertation, Universitas Muhammadiyah Surakarta).

Rukmana, R., Yudirachman, H. 2016. BudiDaya & Pascapanen Tanaman Oat Unggulan. Yogyakarta: Lily Publisher.

Surjowardojo, P., Susilorini, T. E., & Benarivo, V. (2016). Daya Hambat Dekok Kulit Apel Manalagi (Malus sylvestris Mill) Terhadap Pertumbuhan Escherichia coli Dan Streptococcusagalactiae Penyebab Mastitis Pada Sapi Perah. TERNAK TROPIKA Journal of Tropical Animal Production, 17(1), 11-21.

Wasiaturrahmah, Y., dan Jannah, R. 2018. Formulasi Dan Uji Sifat Fisik Gel Hand Sanitizer Dari Ekstrak Daun Salam (Syzygium polyanthum). Borneo Journal Of Pharmasecientech.




DOI: https://doi.org/10.33024/jaf.v6i2.5951

Refbacks

  • Saat ini tidak ada refbacks.


##submission.copyrightStatement##

##submission.license.cc.by-nc4.footer##