PEMBERIAN SUPLEMEN KOLAGEN TERHADAP KADAR GULA DARAH PADA WANITA MENOPAUSE

Dewi Rosalina -  Kebidanan, Universitas Nasional Jln RM Harsono no 1 Jakarta Selatan, Indonesia
Sri Dinengsih* -  Fakultas Ilmu kesehatan-UNAS, Indonesia
Risza Choirunissa -  Kebidanan, Universitas Nasional Jln RM Harsono no 1 Jakarta Selatan, Indonesia
DOI : 10.33024/jkm.v7i1.3130
ABSTRACT GIVING COLLAGENT SUPPLEMENTS ON BLOOD SUGAR LEVELS IN MENOPAUSE WOMEN

 

Background: Menopause is a natural process experienced by every woman aged around 48-54 years. The factors that affect menopause at the beginning are usually due to indiscriminate food consumption so that menopausal women experience diabetes mellitus which is increasing where it is known that blood sugar levels can increase.

Purpose: This study was to determine the effect of collagen supplementation on blood sugar levels in menopausal women suffering from Diabetes Mellitus in the Work Area of the Curug Public Health Center, Tangerang Regency, 2020.

Method: This study was a quasi-experimental study with a One Group Pretest-Postest Design without a control group. The sampling technique used was total sampling. The sample in this study consisted of 20 menopausal women who suffered from diabetes mellitus in June-July 2020.

Results: the results of this study indicated that blood sugar levels in menopausal women before being given collagen supplements were 277.15 and after being given collagen supplements 260.30. The results of the Paired t-test analysis showed that there was no effect of blood sugar levels in menopausal women suffering from diabetes mellitus, before and after giving collagen supplements with a value of Pvalue = 0.471.

Conclusion : the conclusion is that there is no effect of blood sugar levels before and after giving collagen supplements to menopausal women suffering from diabetes mellitus in the Work Area of the Curug Public Health Center, Tangerang Regency, 2020

Suggestion: It is hoped that further research can carry out further research on collagen supplementation in menopausal women on blood sugar levels with a longer / longer study time and add other variables that have not been studied.

 

Keywords: Menopause, Blood Sugar, Collagen.

ABSTRAK

Latar Belakang: Menopause merupakan proses alamiah yang dialami setiap wanita yang berusia sekitar 48-54 tahun, faktor yang mempengaruhi menopause pada awal biasanya dikarenakan konsumsi makanan yang sembarangan sehingga wanita menopause mengalami diabetes mellitus semakin meningkat dimana telah ketahui kadar gula darah dapat meningkat.

Tujuan : Penelitian ini untuk mengetahui pengaruh pemberian suplemen kolagen terhadap kadar gula darah pada wanita menopause yang menderita Diabetes Mellitus di Wilayah Kerja Puskesmas Curug Kabupaten Tangerang Tahun 2020.

Metode : Penelitian ini quasi-experiment dengan rancangan One Group Pretest-Postest Design tanpa adanya kelompok kontrol.Teknik pengambilan sampel yang digunakan adalah total sampling. Sampel dalam penelitian ini berjumlah 20 wanita menopause yang menderita diabetes mellitus pada bulan juni-juli tahun 2020

Hasil penelitian ini menunjukkan bahwa kadar gula darah pada wanita menopause sebelum diberikan suplemen kolagen 277,15 dan sesudah diberikan suplemen kolagen 260,30. Hasil analisis Uji Paired t-test menunjukan bahwa tidak ada pengaruh kadar gula darah pada wanita menopause yang menderita diabetes mellitus,sebelum dan sesudah pemberian suplemen kolagen dengan nilai Pvalue =0,471.

Kesimpulan tidak ada pengaruhkadar gula darah sebelum dan setelah pemberian suplemen kolagen pada wanita menopause yang menderita diabetes mellitus di Wilayah Kerja Puskesmas Curug Kabupaten Tangerang Tahun 2020

Saran : diharapkan untuk penelitian selanjutnya dapat melakukan penelitian lebih lanjut mengenai suplemen kolagen pada wanita menopause terhadap kadar gula darah dengan waktu penelitian yang lebih panjang/lamadan menambahkan variable-variabel lain yang belum di teliti.

 

Kata Kunci :Menopause, Kadar Gula Darah ,Suplemen Kolagen
  1. Alimul,Hidayat A.A., 2010. Metode Penelitian Kesehatan Paradigma Kuantitatif, Jakarta: Heath Books
  2. Ahmad, M. G., Setyaningsih, I., & Trilaksani, W. (2019). Formulasi dan bioaktivitas suplemen tablet berbasis Spirulina dan hidrolisat kolagen kulit ikan nila. Jurnal Pengolahan Hasil Perikanan Indonesia, 22(3), 453-463.
  3. Alves, A. L., Marques, A. L., Martins, E., Silva, T. H., & Reis, R. L. (2017). Cosmetic potential of marine fish skin collagen. Cosmetics, 4(4), 39
  4. Belouafa, S., Bourja, L., Villain, S., Tayane, S., Bennamara, A., & Abourriche, A. (2018). Biocomposite Based on Collagen/Calcium Salts Extraction from Sardine Scales. Smart Application and Data Analysis for Smart Cities (SADASC'18)
  5. Bilek, S. E., & Bayram, S. K. (2015). Fruit juice drink production containing hydrolyzed collagen. journal of functional foods, 14, 562-569
  6. Brownlee M, The Pathobiology of Diabetic Complications, Dabetes , 2005 June ; 54 : 1615-25
  7. Budiman.2011.Penelitian Kesehatan Badung :Refika Aditama
  8. Campos PMMBG, Melo MO, Calixto LS, Fossa MM. 2015. An oral supplementation based on hydrolyzed collagen and vitamins improves skin elasticity and dermis echogenicity: a clinical placebo controlled study. Clin Pharmacol Biopharm. 4(3):1-6.
  9. Ceriello A, The Hyperglicemia-Induced “Metabolic Memory” : The new Challenge for the Prevention of CVD in Diabetes, Rev Esp Cardiol Supl. 2008;8:11-7C
  10. Chandra, B. Metodolog iPenelitian Kesehatan.
  11. Erensoy et al, Effects of ACE inhibition on expression of type IV collagen and laminin in renal glomeruli in experimental diabetes, Acta Histochem, 2004; 106 (4): 279-87
  12. Fan J, Zhuang Y, Li B. 2013. Effect of collagen and collagen hydrolysate from jellyfish umbrella on histological and immunity changes of mice photoaging. Nutrients. (5):223-233
  13. Felician, F. F., Xia, C., Qi, W., & Xu, H. (2018). Collagen from marine biological sources and medical applications. Chemistry & biodiversity, 15(5), e1700557.
  14. Firdausiya, F. (2011). Hubungan Penyakit Diabetes Melitus Tipe 1 Dengan Usia Awal Menopause
  15. Hong GP, Min SG, Jo YJ. 2019. Anti-oxidative and anti-aging activities of porcine byproduct collagen hydrolysates produced by commercial proteases:
  16. Hasanah,Nunung (2014) Pemberian Ekstrak Etanol Daun Salam Untuk Menurunkan Ekspresi Fibronektin Mesangial Tikus Sprague Dawley DM. Masters thesis, Master Program of Biomedical Science
  17. Hashim, P., Ridzwan, M. M., Bakar, J., & Hashim, M. D. (2015). Collagen in food and beverage industries. International Food Research Journal, 22(1), 1
  18. Hongdong, S., Bo, Li. (2017) Beneficial Effects of Collagen Hydrolysate: A Review on Recent Developments. Biomed J Sci & Tech Res, 1(2): 1-4
  19. Katili, A. S. (2009). Struktur dan fungsi protein kolagen. Jurnal Pelangi Ilmu, 2(5).
  20. Karyati, S. (2016). Usia menopause dan Kejadian Diabetes melitus. Jurnal Ilmu Keperawatan dan Kebidanan, 7(2).
  21. Kumar, S., Sugihara, F., Suzuki, K., Inoue, N., Venkateswarathirukumara, S. (2014) A double blind Placebo controlled, randomized, clinical study on the effectiveness
  22. Lestari, I. D. (2013). Pengaruh spesies rumput laut dan kadar gula terhadap kualitas nata sebagai materi booklet untuk masyarakat pesisir/Indah Lestari Dwi (Doctoral dissertation, Universitas Negeri Malang).
  23. Litchenco S, Kempka AP, Prestes RC. 2017. Profiles of enzymatic hydrolysis of different collagens and derivating over time. Revista Brasileira de Tecnologia Agroindustrial. 11(1): 2165-2185
  24. Nongonierma, AB., FitzGerald, RJ. (2014) Susceptibility of milk proteins derived peptides to Dipep
  25. Notoatmodjo,S. 2012. Metodologi Penelitian Kesehatan. Jakarta: RinekaCipta
  26. Nursalam. 2013. Metodologi Penelitian Ilmu Keperawatan: Pendekatan Praktis : Jakarta : Salemba Medika.
  27. Nursalam. 2008. Konsepdan Penerapan MetodologiPenelitian Ilmu Keperawatan. Jakarta: Salemba Medika
  28. Riccardi, G., Rivelles, AA. (1991) Effect of dietary fibre and carbohydrate on glucose and lipoprotein
  29. Sari, W., Indrawati, L., & Basuki Dwi Harjanto, M. M. (2012). Panduan lengkap kesehatan wanita. Penebar PLUS+.
  30. Santoso, H., & Ismail, H. (2009). Memahami krisis lanjut usia. BPK Gunung Mulia.
  31. Sofian.2011.Sinopsis Obstetrijilid2.Jakarta : EGC
  32. Sugiyono. 2012. Metode Penelitian Kuantitatif Kualitatif dan R&D. Bandung: Alfa beta
  33. Stipcevic, T., Piljac, J., & Berghe, D. V. (2006). Effect of different flavonoids on collagen synthesis in human fibroblasts. Plant foods for human nutrition, 61(1), 27-32.
  34. Waluyo, S, & Putra, M.B. (2010). The Book Of Antiaging Rahasia Awet Muda Mind-Body-Spirit. Jakarta : PT Elex Media Komputindo
  35. Whiteside Catharine snd Dlugosz, John A, mesangial Cell protein kinase C isozyme activation in the diabetic mileu, Am J Physiol Renal Physiol, 2002; 282: F975-80 effect of hydrolysis and ultrafiltration. Molecules. 24:1-14.
  36. Zhu, C., Li, G., Peng, H., Zang, F., Chen, Y., Li, Y. (2010) Treatment with marine collagen peptides modulates glucose and lipid metabolism in Chinese patients with
  37. Zizadeh Fuad N et al, Stimulation of Collagen Gene Expression and protein Synthesis in Murine mesangial Cells by High Glucose is Mediated by Autocrine Activation of Transforming Growth Factor-ß, J. Clin. Invest, 1994 February; 93: 536-42

Open Access Copyright (c) 2021 Jurnal Kebidanan Malahayati

Policies

Submissions

Other

Focus and Scope
Section Policies
Peer Review Process
Publication Frequency
Open Access Policy		Online Submissions
Author Guidelines
Copyright Notice
Privacy Statement
Author Fees		Journal Sponsorship
Journal History
Site Map
About this Publishing System
JKM (Jurnal Kebidanan Malahayati)