NEKROLISIS EPIDERMAL TOKSIK DENGAN INFEKSI HIV STADIUM IV : LAPORAN KASUS

Sissy Sissy, Novita Indah Permatasari, Zahwa Arsy Azzahra, Ismalia Husna

Sari


Abstrak: Nekrolisis Epidermal Toksik Dengan Infeksi HIV Stadium IV:
Laporan Kasus. Nekrolisis epidermal toksik (NET) adalah suatu reaksi
mukokutaneus yang disebabkan oleh obat. Reaksi ini bersifat akut dan dapat
mengancam jiwa yang ditandai dengan adanya nekrosis berat dan pelepasan
epidermis. Berikut dilaporkan satu kasus seorang laki-laki 31 tahun dengan luas
permukaan tubuh yang terlibat berupa purpura disertai adanya skin detachment
dengan luas permukaan tubuh yang terlibat sebesar 36% serta adanya keterlibatan
tiga lesi pada membran mukosa yaitu pada mukosa mata, bibir dan kelamin dengan
gejala prodromal berupa demam sebelum timbulnya lesi dan didapatkan tanda
Nikolsky (+), antibodi HIV dengan hasil reaktif sehingga diadaptkan diagnosis
nekrolisis epidermal toksik dengan infeksi HIV stadium IV. Pada kasus, penderita
mendapatkan terapi berupa eliminasi obat yang dicurigai, pemberian deksametason
10 mg-10 mg-10 mg intravena yang diturunkan hingga menjadi metilprednisolon
sediaan oral 16 mg tiap 12 jam dalam waktu 14 hari, dan dua hari kemudian
diturunkan kembali dosisnya diberikan konseling informasi dan edukasi (KIE).


Kata Kunci


Nekrolisis Epidermal Toksik; Lesi; HIV

Teks Lengkap:

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Referensi


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DOI: https://doi.org/10.33024/jikk.v10i5.10162

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