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Pengaruh Kadar Profil Lipid, Asam Urat, Indeks Massa Tubuh, Tekanan Darah, dan Kadar Gula Darah Terhadap Penurunan Kapasitas Vital Paru pada Pekerja Usia Produktif
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ABSTRACT
Decreased lung function is a common health problem that affects millions of people worldwide. The prevalence of decreased lung function in the general population has increased from 11.2% to 28.8% in individuals over the age of 50 years. The exact mechanism of these relationships is not fully understood. This study aims to determine the effect of obesity, hypertension, dyslipidemia, hyperuricemia, and diabetes mellitus on the decline in lung function among working-age workers. This research is a cross-sectional study carried out at the Kalam Kudus Foundation in the period of May 2023 involving productive age respondents aged 18 to 60 years. The minimum sample size required in this study is 50 respondents according to the rule of thumb formula. Descriptive data analysis in the form of centralized data distribution for quantitative data and proportion (%) for qualitative data. Analytical data analysis uses the Linear Regression method, enter method to see which factor has the strongest influence on the dependent variable. The results of the linear regression statistical test revealed that only the Low-Density Lipoprotein (LDL) level variable had a significant role in affecting lung vital capacity (OR: 0.433; p-value: 0.030). From the analysis results, it was found that LDL levels significantly affect the vital capacity of the lungs. Further research is needed to assess other factors that affect lung vital capacity.
Keywords: Lung Vital Capacity, Lipid Profile, Uric Acid, BMI, Blood Pressure, Blood Glucose Level.
ABSTRAK
Penurunan fungsi paru-paru adalah masalah kesehatan umum yang mempengaruhi jutaan orang di seluruh dunia. Prevalensi penurunan fungsi paru pada populasi umum mengalami peningkatan dari 11,2%, menjadi 28,8% pada individu di atas usia 50 tahun. Mekanisme yang tepat hubungan-hubungaan ini tidak sepenuhnya dipahami. Penelitian ini bertujuan untuk melihat bagaimana pengaruh dari obesitas, hipertensi, dislipidemia, hiperurisemia, dan diabetes mellitus terhadap penurunan fungsi paru di kalangan pekerja usia produktif. Penelitian ini merupakan penelitian potong lintang yang dilaksanakan di Yayasan Kalam Kudus pada periode bulan Mei 2023 dengan mengikutsertakan responden usia produktif berusia 18 hingga 60 tahun. Besar sampel minimum yang dibutuhkan pada penelitian ini adalah 50 responden berdasarkan rumus rule of thumb. Analisa data deskriptif berupa sebaran data terpusat untuk data kuantitatif dan proporsi (%) untuk data yang bersifat kualitatif. Analisa data analitik menggunakan metode Regresi Linear, enter method untuk melihat faktor mana yang memiliki pengaruh terkuat dalam mempengaruhi variabel tergantung. Hasil uji statistik regresi linear mengungkapkan bahwa hanya variabel kadar Low Density Lipoprotein (LDL) yang berperan signifikan dalam mempengaruhi kapasitas vital paru (OR: 0,433; p-value: 0,030). Dari hasil analisis didapat kadar LDL mempengaruhi kapasitas vital paru secara signifikan. Penelitian lebih lanjut diperlukan untuk menilai faktor lain yang mempengaruhi kapasitas vital paru.
Kata Kunci: Kapasitas Vital Paru, Profil Lipid, Asam Urat, IMT, Tekanan Darah, Kadar Gula Darah
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DOI: https://doi.org/10.33024/mnj.v5i8.10414
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